Are there real-world uses today for multi-year Bitcoin timelocks?

I’ve been experimenting with Bitcoin scripts that rely heavily on CLTV, and I’m considering setups intended not to be spendable for many years.

I’m trying to understand the real-world risks of building around long timelocks.

If anyone has experience with long-horizon timelocks, inheritance setups, or vault-style constructions that were meant to last years, I’d really appreciate hearing what actually matters in practice.