should I take a new opportunity and pay cut?

so I currently make about 68,000 a year. My job right now is not a dream job but more a surviving job. I am married and our combined is about 135,000. Now, I want to start pursing my health career and in order to get my foot in the door, the new job opportunity would push me back to 30-40k a year. would you take it?
we are already thinking of selling our house and living below our means, so that we aren’t stretched thin. what do you think? i’m scared of regretting my decision.